请改写下列句子表达避免出现与原文连续4个单词重复：Alzheimer’s disease AD is characterized by the accumulation of intracellular accumulation of insoluble hyperphosphorylated tau proteins p-tau and abnormal protein deposits o
AD is distinguished by the buildup of insoluble p-tau proteins and abnormal protein deposits, known as plaques, which consist of Ab peptides (Ab1–40 and Ab1–42).
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