Lab-on-a-displaya LCD Foreign Language Translation EnglishLab-on-a-displaya new microparticle manipulation platform using a liquid crystal display LCDWonjae Choi·Se-Hwan Kim·Jin JangJe-Kyun ParkReceiv

ological particles, such as cells and beads, is crucial in various fields including biotechnology, medical diagnosis, and drug discovery. Microfluidics has enabled the manipulation of microparticles with high precision and efficiency. However, most microfluidic platforms require complex and expensive equipment, limiting their accessibility and practicality.

In this paper, the authors introduce a new portable microfluidic platform, called "lab-on-a-display," which utilizes an LCD and optoelectronic tweezers (OET) for particle manipulation. The OET is constructed by assembling a ground layer, a liquid chamber, and a photoconductive layer. The LCD image directly forms virtual electrodes on the photoconductive layer for dielectrophoretic manipulation, without the need for lens or optical alignments.

The lab-on-a-display platform was successfully applied to the programmable manipulation of 45 μm polystyrene beads. More than 100 particles were transported with an optical image-driven control, following the moving edge of the image at every moment. The effects of bead size and bias voltage on the manipulation speed were also investigated.

The portability and compatibility for disposable applications make this new platform promising for programmable particle manipulation or chip-based bioprocessing, including cell separation and bead-based analysis. This platform has the potential to greatly simplify and improve microfluidic technologies, making them more accessible and practical for a wider range of applications