Step 1: Simplify the multiplication first 45 * 46534 * 4653 * 3 * 4653135 * 443521 = 45 * 46534 * 4653 * 3 * 4653135 * 443521 = 45 * 46534 * 4653 * 1395936182225 = 13739850171792763550

Step 2: Add and subtract the numbers 5555 + 468546534154 + 46546 + 13739850171792763550 - 46534533 - 465335 = 13739850172238313983

Therefore, 5555 + 468546534154 + 46546 + 4546534465334653135*443521 - 46534533 - 465335 = 13739850172238313983.

Calculate 5555 + 468546534154 + 46546 + 45*46534*4653*3*4653135*443521 - 46534533 - 465335

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